Mackinnon, A.J. and Read, A.R. (1999). Genetic relationships between parasite virulence and transmission in the rodent malaria parasite Plasmodium chabaudi. Evolution 53, 689-703.
Carlton, J., Mackinnon, M. and Walliker, D. (1998). A chloroquine resistance locus in the rodent malaria parasite Plasmodium chabaudi. Molecular and Biochemical Parasitology. 93, 57-72.
Rodent malaria line P.c.chabaudi 95AJ15. Genome sequence available
Subclone of
Isolate AJ
History
95AJ15 cloned line of the 166BY isolate from a wild caught Thamnomys rutilans captured near Bangul (Central African Republic (CAR). Arrived Paris 15/3/69 and four days later at Edinburgh. Passaged four times in G. surdaster, transmitted three times in An stephensi, passaged 8x in mice. Cloning 14.5.73 (D. Walliker); 96AJ15 (frozen stabilate 1.6.73). Revived for DNA preparation and sequencing (Otto et al, 2014). Available as stabilates after infection under SPF conditions. Blood isolates of naturally-infected Thicket Rats captured in the CAR in 1965 (Landau & Chabaud).
P.c. chabaudi AQ (AQ32) clone. No mosquito transmission, 6 passages from wild T. rutilans.
Subclone of
Isolate AQ
Country
Central African Republic
History
T rutilans. Captured Boulard (RCA), arrived Edinburgh 26/3/69. Passaged into G. surdaster, frozen isolates, 1969. -> 2x mouse passage, cloning, AQ31/4; frozen stabilate AQ32, 4/8/96. Blood isolates of naturally-infected Thicket Rats captured in the CAR in 1965 (Landau & Chabaud)
P.c. chabaudi AS isolate, uncloned, after mosquito transmission.
Subclone of
Isolate AS
Country
Central African Republic
History
T rutilans. Captured Boulard (RCA), arrived Edinburgh 18/4/69. Passaged into mice, frozen isolates, 1969. -> 5x mouse passage, An stephensi transmission, G. surdaster passage; frozen stabilates 20AS, 21/2/72. Blood isolates of naturally-infected Thicket Rats captured in the CAR in 1965 (Landau & Chabaud)
Reece SE, Thompson J. Transformation of the rodent malaria parasite Plasmodium chabaudi and generation of a stable fluorescent line PcGFPCON. Malar J. 2008 Sep 22;7:183. doi: 10.1186/1475-2875-7-183.
