GST Type Recombinant Plasmodium protein Description Glutathione-S-transferase Derived from S. japonicum Fusion partner None Links Smith and Johnson, 1988 References Smith and Johnson, 1988
MSP-1 (3D7 BL2) Type Recombinant Plasmodium protein Description MSP-1 3D7 Block 2 antigen fused to GST Subclone of MSP-1 gene from 3D7 Derived from P. falciparum Fusion partner GST Country Netherlands/Africa Source David Cavanagh History MSP-1 Block 2 protein. GST fusion protein belonging to the K1 Block 2 serotype of MSP-1. Contains SAQSGA repeats. Monoclonal 12.2 recognises this protein (see antibodies section of the reagents list). UK Biosafety level 1 Availability Available. Enquire. References Cavanagh DR, McBride JS. Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoite surface protein 1. Mol Biochem Parasitol. 1997 Apr;85(2):197-211.Map of all MSP-1 Block 2 proteins (pdf)MSP1 map proteins all(pdf)
MSP-1 (DWK1 BL2) Type Recombinant Plasmodium protein Description MSP-1 K1 serotype Block 2 antigen derived from the blood of a donor from Daraweesh, Sudan. Fused to GST. Derived from P. falciparum (patient isolate) Fusion partner GST Country Sudan Source David Cavanagh UK Biosafety level 1 Availability Available. Enquire. References Cavanagh et al., (1998) A Longitudinal Study of Type-Specific Antibody Responses to Plasmodium falciparum Merozoite Surface Protein-1 in an Area of Unstable Malaria in Sudan. J. Immunol. 161:347-359
MSP-1 (MAD20 BL2) Type Recombinant Plasmodium protein Description MSP-1 MAD20 serotype Block 2 region antigen fused to GST Derived from P. falciparum isolate MAD20 MSP-1 gene Fusion partner GST Country Papua New Guinea (MAD20 isolate) Source David Cavanagh History MSP-1 Block 2 protein. GST fusion protein belonging to the MAD20 Block 2 serotype of MSP-1. Contains SGGSVA repeats. UK Biosafety level 1 Availability Available. Enquire. References Cavanagh DR, McBride JS. Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoite surface protein 1. Mol Biochem Parasitol. 1997 Apr;85(2):197-211.Map of all MSP-1 Block 2 proteins (pdf)MSP1 map proteins all(pdf)
MSP-1 (PA17 BL2) Type Recombinant Plasmodium protein Description MSP-1 Palo Alto Block 2 region antigen fused to GST. Derived from P. falciparum (isolate Palo Alto 17) MSP-1 gene Fusion partner GST Country Uganda (PA17/Palo Alto isolate) Source David Cavanagh UK Biosafety level 1 Availability Available. Enquire. Links Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoi… References Cavanagh DR, McBride JS. Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoite surface protein 1. Mol Biochem Parasitol. 1997 Apr;85(2):197-211.
MSP-1 (RO33 BL2) Type Recombinant Plasmodium protein Description MSP-1 RO33 Block 2 region antigen fused to GST Derived from P. falciparum RO33 isolate Fusion partner GST Country Ghana (RO33 isolate) Source David Cavanagh UK Biosafety level 1 References Cavanagh DR, McBride JS. Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoite surface protein 1. Mol Biochem Parasitol. 1997 Apr;85(2):197-211.
MSP-1 (Wellcome BL2) Type Recombinant Plasmodium protein Description MSP-1 Wellcome isolate Block 2 region antigen fused to GST Derived from P. falciparum (isolate Wellcome/Liverpool) MSP-1 gene Fusion partner GST Country Nigeria (Wellcome-Liverpool isolate) Source David Cavanagh UK Biosafety level 1 References Cavanagh DR, McBride JS. Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoite surface protein 1. Mol Biochem Parasitol. 1997 Apr;85(2):197-211.
MSP-1 hybrid Type Recombinant Plasmodium protein Description Synthetic hybrid antigen containing all 3 serotypes of Plasmodium falciparum MSP1 Block 2 plus MSP-1 Block 1 Subclone of MSP-1 gene from 3D7 Derived from P. falciparum Fusion partner untagged protein Source David Cavanagh UK Biosafety level 1 Availability Available. Enquire. References Cowan et al., (2011) PLoS One 6(10): e26616. doi:10.1371/journal.pone.0026616
MSP-2 (7G8 5/7) Type Recombinant Plasmodium protein Description MSP2 Region 1 repeat antigen type A Derived from P. falciparum (isolate 7G8) Fusion partner GST Country Brazil Source Dr. Jana McBride History Type A repeat sequence antigen from 7G8 parasite. Clone using primers 5 and 7, hence the name. UK Biosafety level 1 Availability Available. Enquire. References MSP-2 proteins map(pdf)
MSP-2 (CH12/12 5/7) Type Recombinant Plasmodium protein Description MSP2 Region 1 repeat antigen type A Derived from P. falciparum isolate CH12/12 Fusion partner GST Country Thailand Source David Cavanagh UK Biosafety level 1 Availability Available. Enquire. References MSP-2 proteins map(pdf)
