Recognises the Block 3 region of MSP-1, specifically dependent on the presence of (124-R) to (E-284) version of Block 3. This sequence found in the FCB1 isolate (see Miller et al 1993 for details of MSP-1 sequence comparisons- MSP-1 residue numbering in t
Subclone of
Fusion 13
Isotype
IgG1
Target
MSP-1 Block 3 (Wellcome)
Fusion partner
NS1
Source
Dr. Jana McBride
History
Mouse monoclonal antibody raised by immunisation with schizont extracts
Recognises the MAD20 form of MSP-1, binding to an allele specific epitope within the 1078-NSLNNPHN to RVSGSSGS-1251 sequence within the Block6-16 region
Subclone of
Fusion 9
Isotype
IgG1
Target
MSP-1 (MAD20 type)
Fusion partner
NS1
Source
Dr. Jana McBride
History
Produced by immunisation of mice with P. falciparum schizonts (Thai PB1 isolate as immunogen)
Recognises the Block 3 region of MSP-1, specifically dependent on the presence of (127-Q) to (Q-287) version of Block 3. This sequence found in the MAD20/RO33 isolates (see Miller et al 1993 for details of MSP-1 sequence comparisons- MSP-1 residue numberi
Subclone of
Fusion 9
Isotype
IgG2b/kappa
Target
MSP-1 Block 3
Source
Dr. Jana McBride
History
Mouse monoclonal antibody raised by immunisation with schizont extracts
